BIOLOGY 1A03 Study Guide - Final Guide: Central Dogma Of Molecular Biology, Sigma Factor, Consensus Sequence
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BIOLOGY 1A03 Full Course Notes
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Dna template: rho factor destabilizes the interaction b/w rna and dna template, releasing the transcript & complex. In eukaryotes, transcription and translation are physically separated by nuclear membrane. In eukaryotes, primary mrna transcript must be modified in the nucleus to produce mature mrna. Termination of transcription: rna polymerase ii depends on a poly(a)-dependent mechanism of termination, termination of transcription is coupled with mrna maturation, rna polymerase i- transcription ends through a eukaryotic termination factor like prokaryotic. Rho-dependent: rna polymerase iii- transcription ends after transcription of a termination sequence like the rho- independent. If splicing does not occur, the protein may not contain the correct sequence of aa: mature of mrna is exported through nuclear pores and introns don"t exist in prokaryote mrna. Rna splicing: spliceosomes- composed of snrnps that are made up of small rnas and proteins, catalyze the recognition of splice sites (short nucleotide sequences) at each end of the intron, 1.