KINESIOL 4B03 Study Guide - Final Guide: Low-Density Lipoprotein, User Friendly, Genetic Predisposition

• School: McMaster University
• Department: Kinesiology
• Course: KINESIOL 4B03
• Professor: Janet Currie

Document Summary

Assumes causal role between condition/behavior and the pathogenesis of cvd research focuses on mechanisms of how a causes b - condition/behaviour cvd: randomized controlled trials (rct): modify behaviour, watch result. Change a what happens to b eg. treatment of a, does it prevent b: cross-sectional/observational trials: link between condition/behaviour and cvd. Measure a and b and see if there is a link. A causes atherosclerosis b (cvd disease) Criteria for establishing something as a risk factor. Temporal relationship between exposure (to risk factor / behaviour) and disease. Strength of association gauge likelihood of getting disease, weak or strong. Dose-response relationship more risk factor / behaviour = more likely to get disease. Reproducible make sure the measurement is reliable (get the same result every time) Biologic plausibility needs to be biologically sound. Reduction of risk with cessation of exposure stopping exposure decreases risk.