PHGY 350 Final: PHGY350 Post-Midterm Study
9 Nov 2016
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Document Summary
Secrete hormones directly into the blood; act at receptors (often on other endocrine glands) May be exerted by a nonhormonal signal. Application: appropriate feedback response (or lack thereof) provides clues to the pathophysiology. Parathyroid hormone (pth) increase ca2+ in the circulation. Negative feedback keep [ca++] in normal range. If ca++ is elevated and pth is low, rules out hyperthyroidism. Bets treatment choice is hormone deficiency dictated by cause. Shrink androgen or estrogen dependent tumours by shutting off gonadal production of steroids. Radioactive iodine for treating thyroid gland tumour. Inadequate insulin production by the beta cells of the pancreas. Inadequate = normal or elevated (but indufficiency because of insensitivity; type 2) Sweet flow (gr) referring to sugar in urine. Inadequate insulin secretion from pancreas or insensitivity to insulin leads to: Adult onset diabetes (can occur in children) 9% prevalence n adults >20 yo (1 in 3 by 2050) Weight loss and fatigue (starvation state educed metabolism)
