NU FS305 Study Guide - Final Guide: Neural Tube Defect, Neural Tube, Homoserine

• School: University of Alberta
• Department: Nutrition and Food Sciences
• Course: NU FS305
• Professor: Donna Vine

Document Summary

Folate has 4 main functions: dna synthesis, 1-carbon metabolism, amino acid metabolism, vitamin b12 activation to a coenzyme. The activation of folate happens when b12 cleaves off the methyl group from folate. Folate is activated because of this loss while b12 keeps the methyl group and it is also activated because of this. B12 are active and ready for dna synthesis. For adults the ear is 320 ug dfe/day, the rda is 400 ug dfe/day and ul is. The exception here is pregnant women who have a rda of 600ug/day to help protect the baby against spine abifita. The tul applies only to supplements and fortified foods, or a mixture of the two. The bioavailability from natural sources is 50% but from synthetic sources 100% of the folic acid added is bio available. This can be concerning because rda for pregnant women is close to the tul, so they must abide by supplement guidelines.