BIOL301 Study Guide - Pulmonary Circulation, Sickle-Cell Disease, Bone

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12 Apr 2014
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Circulatory system is made up of: cardiovascular system (double circuit pulmonary and systemic) Cardiovascular system: because humans are multi-cellular organisms a system is needed to distribute critical cargo (gases, nutrients) throughout the body. From external environment to the tissues, between and from the tissues to the external environment: this is accomplished by the heart, blood vessels and blood. Contains: ground substance/fluid plasma, buffy coat in between plasma and rbcs leukocytes and platelets, formed elements cells of the blood (erythrocytes) Plasma: primarily water (~90%, contains dissolved material: proteins (albumin, globulins, fibrinogen), electrolytes (e. g. , na), nutrients (e. g. , glucose), gas (e. g. , co2, makes up 50% of blood. Formed elements: blood cells are scattered in the plasma, erythrocytes rbcs, biconcave discs that have no nucleus anucleate, main protein hemoglobin. Gas transport: makes up 40-50% of blood, originates in red bone marrow and lives up to 120 days. Leukocytes wbcs: less than 1% of blood, nucleated, can change their shape.