BIOL 112 Study Guide - Final Guide: Small Nuclear Rna, Rna Splicing, Nucleic Acid Double Helix

• School: UBC
• Department: Biology
• Course: BIOL 112
• Professor: Karen Smith

Document Summary

Transcription and translation occur in the cytoplasm. Needs sigma factor to bind to promoter/rna pol. Rna pol starts transcription at +1 site. * separation of transcription and translation allows for different levels of gene expression. Initiation: aug (codon), and aatrna brings met aa. Re(cid:395)ui(cid:396)es i(cid:374)itiatio(cid:374) fa(cid:272)to(cid:396)s (cid:894)shi(cid:374)e dalga(cid:396)i(cid:374)o o(cid:396) 5"(cid:272)ap(cid:895) whi(cid:272)h (cid:396)e(cid:272)(cid:396)uit small subunit of ribosome. Once the small subunit and initation factors reach the aug codon, large subunit attaches, initiation factors are released (cid:894)shi(cid:374)e dalga(cid:396)i(cid:374)o (cid:894)(cid:271)a(cid:272)te(cid:396)ia(cid:895) 5" cap (eukaryotes)) Elongation: aatrnas attach aa to anticodon down the reading frame and polypeptide chain is lengthened. *aa a(cid:396)e added 5" to (cid:1007)" (cid:894)a(cid:373)i(cid:374)o te(cid:396)(cid:373)i(cid:374)us ca(cid:396)(cid:271)o(cid:454)(cid:455)l te(cid:396)(cid:373)i(cid:374)us . Aminoacyl trna synthetases attach the correct aa to the specific trnas based on the anticodon of the trna. * responsible for translating the codon sequence into a specific aa. * catalyzes covalent bond between aa and trna (h-bond.