MICB 202 Study Guide - Final Guide: Rna-Dependent Rna Polymerase, Mhc Class I Polypeptide-Related Sequence B, Reverse Transcriptase
Document Summary
Micb 202 topic 1 viruses: molecular diversity, properties and pathogenicity: provide a definition of the term virus , and describe the basic structures of viruses. Genetic information (nucleic acid) surrounded by a protein coat. Some also contain external structures (e. g. , spikes) and an envelope of phospholipids. Cannot synthesize proteins on their own. require host cells to reproduce. cannot synthesize their own atp or amino acids or nucleotides. Type of host cell infected (species specific, cell/tissue specific). Genetic material (ssdna or dsdna or ssrna or dsrna). Replication strategies: where the genome is replicated, replication cycle (lytic, persistent, latent): explain the terms (+) rna and ( ) rna, and polyprotein. Dna viruses that replicate their genomes in the cytoplasm must have at least 3 genes: own dnap, Own rnap, and capsid protein genes: rna viruses (except retroviruses) same problem for all: there is no cellular enzyme that can read rna as a template to make rna.