NURS 310 Study Guide - Final Guide: Inotrope, Central Nervous System Depression, Glucosidases
Document Summary
Acts on kidney tubule to decrease reabsorption of sodium, which brings water with it. Decrease in blood volume and decrease in bp. Selectively blocks calcium channels in myocardial + vascular smooth muscle, including coronary arteries. Decreases o2 demands on heart, increases cardiac output and decreases bp. Selective to alpha-1 receptors in vascular smooth muscle. Dilates arteries and veins causing rapid decrease in. Direct vasodilator direct vasodilation of vascular smooth muscle, decreased bp. Decrease angiotensin ii and aldosterone to decrease bp. May require 2-3 weeks to reach max efficacy. Decrease in hr and bp (which decreases afterload and workload of heart). Acts directly and selectively on veins to cause vasodilation. Decreases venous return (preload), thus decreases cardiac workload. Reduces symptoms, slows progression and increases exercise tolerance. Improved cardiac output leads to decreased pulmonary congestion and peripheral edema. (cid:313) contractility of myocardial contraction (+ inotropic action). Ca release, creating (cid:313) force of contraction & cardiac output.
