PHA3112- Midterm Exam Guide - Comprehensive Notes for the exam ( 91 pages long!)

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Pharmacology: the study of drugs and their interactions with living systems. Study of the physical and chemical properties of drugs. Knowledge of the history, sources and uses of drugs. Studies the effects of drugs on a body"s organ systems (physiology, anatomy) Studies the molecular composition of a drug and the body"s effect on drug structure (biochemistry) Studies the effects of a drug on human behaviours (psychology) Clinical pharmacology: the study of drugs in humans, in patients as well as in healthy volunteers( during new drug development) pharmacology is very multidisiplinary (chemistry, physiology, anatomy, psychology, biochemistry) *get from slides. Pharmacology informs all aspects of clinical drug use. Reasons for giving a particular drug to a particular pt. Rationale for selection of dosage, route, and schedule of administration. No 2 pt"s will respond identically tom same drug regimen. >genetic factors alter drug metabolism unique drug reactions. Prescribed dose administered dose concentration at sites of action intensity of responses.