Biochemistry 2280A Study Guide - Midterm Guide: Amine, Hydrogen Bond, Cell Nucleus

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Synthesized by enzymes that are genetically encoded. Through transcription and translation: amino acids. Proteins are composed of amino acids based on the genetic code. Dna can encode 20 different amino acids the make up proteins (memorize!!) Four classes: polar - charge, polar + charge, polar uncharged, non-polar. Consists of a carbon bonded to an amino group, carboxyl group, hydrogen, and r group. Amino acids (but one) have stereoisomers in either d or l forms, but proteins only contain l - All of humans amino acids are exclusively of the l configuration. Every amino acid has a 3-letter abbreviation and a 1 letter code. Amino acids contain ionizable groups that are the weakly acidic or basic groups present. The ionization of a group changes as the hydrogen ion concentration (ph) changes because of the association/dissociation of protons within the group. For acidic groups, lowering the ph (increasing h+) will drive the ka equilibrium to the left, decreasing ionization.

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