Biochemistry 2280A Final: BIOCHEM2280 - FINAL EXAM McLachin's Lectures (Topics 18 - 21).docx

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Topic 18 introduction to dna & rna. Deoxyribonucleic acid (dna): carries genetic material, the information passed from parents to offspring that is required to produce an organism. Ribonucleic acid (rna): template for producing proteins (mrna), makes up much of ribosome (rrna), carries amino acids to ribosome (trna) protein synthesis. Building blocks of rna are ribonucleotides which is composed of three parts: sugar (ribose), nitrogenous base, and a phosphate. Rna is a linear polymer composed of ribonucleotide monomers. Deoxynucleotide is where the ribose is deoxyribose, 2"c has lost its oh. When making rna and dna, sugar is always in the configuration. Nucleoside: sugar joined to a nitrogenous base: cytidine (nucleoside): cytosine + ribose (via n-glycosidic bond) Nucleotide: all 3 groups: sugar, base, phosphate: adding a phosphate to the nucleoside creates a nucleotide (cytidine. + monophosphate: attached to the 5"c position of the sugar by a phosphoester linkage. Atp is a ribonucleotide, also used to make rna.

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