BIOL 2040 Study Guide - Retrovirus, Oncogene, Reverse Transcriptase
1 Feb 2013
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Document Summary
Using a radioactive probe, they followed a similar system to hershey and chase. By dna hybridization experiment: unaffected chicken in human cells contain homologues of src in the genomes, v-src of rsv was a mutated version of the cellular c-src gene. Proto-oncogene the cellular precursor of the retroviral transforming genes: non-mutated form (these are the cells we use all the time) By some error or other transductions, there are errors that create the mutated form: via reverse transcription (w/ reverse transcriptase) Proto-onc affected by virus mutation replication of affected cells: v-onc occurs after viral infection.
