BIOL 4330 Study Guide - Midterm Guide: Iron-Deficiency Anemia, Bone Marrow, Myelocyte
Document Summary
1 of 4 types of connective tissue (cartilage, bone, blood, fat: only liquid total volume is around 5l, heart rate is around 72 bpm, ejection fraction 72 ml/beat, total blood is moved per min. Main constituents: plasma (fluid, erythryocytes (rbcs, non-adherent, free-floating, synth hemoglobin, carry o2, leukocytes (wbcs, combat infection, platelets, clotting. Immune component: most of total, mono, minor frac, pre-mature, turn to macrophages, cells that will divide, neutrophils, look for viruses. Development of cellular component of blood (hematopoiesis: very complicated and developed in a step-wise, orderly nature, how rbcs are made, common myeloid progenitor megakaryocyte erythroid progenitor erythrocyte. Progenitor rbcs: require specific growth signals, occur in temporarily fashion, transcription factors are black and soluble factors are blue. If they do(cid:374)"t re(cid:272)ei(cid:448)e sig(cid:374)al i(cid:374) appropriate ti(cid:373)e, the(cid:455) (cid:449)ill apoptosis. Erythropoiesis: how red blood cells are made, average count of rbcs is around 5x10^12 cells per year, around 25 trillion rbcs circulating at any given time.
