CAS BI 108 Study Guide - Final Guide: Active Transport, Lipid Bilayer, Passive Transport

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The organization of these phospholipids creates a semi-permeability that allows for the membrane to choose what goes in and what comes out of the (cid:272)ell. Alo(cid:374)e, the phospholipid (cid:271)ila(cid:455)e(cid:396) allo(cid:449)s fo(cid:396) s(cid:373)alle(cid:396), (cid:862)fat solu(cid:271)le(cid:863) e(cid:374)tities to f(cid:396)eel(cid:455) pass i(cid:374) and out. These entities consist of small, nonpolar and uncharged molecules. These small uncharged molecules are able to surpass the hydrophobic interior of the phospholipid bilayer- successfully permeating into the cell. However, to account for the larger, polar and charged species that cells need for metabolic function, cells have developed a system of proteins that are non-covalently embedded into the bilayer. There are two types of proteins that present in the bilayer: integral proteins and peripheral proteins. Integral proteins contain hydrophobic regions that interact with the interior (nonpolar, hydrophobic) region of the bilayer, and hydrophilic regions that stretch extracellularly and can interact with various substances outside the cell.

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