HS 415 Study Guide - Quiz Guide: B-Cell Chronic Lymphocytic Leukemia, Hematology, Metastasis

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Document Summary

Thought to occur after mutations in the dna of blood cells. Affects blood forming organs: bone marrow, lymph nodes and spleen. Defined by an increase in production of new wbc"s that do not properly function, thus, causing a decrease in production of rbc"s and platelets. Classified by how long it progresses, and which wbc type is affected. (see below) Abnormal immature blood cells cannot perform normal function, rapidly multiply and disease progresses quickly. Involves more mature blood cells, can cause over or under production of cells, multiply slowly causing disease to progress slowly. Affects the lymphoid cells that forms lymphatic. Affects myeloid cells that produce rbcs tissue that makes up the immune system. Acute lymphocytic leukemia (all): most common in children, ~6,000 per year. Acute myelogenous leukemia (aml): most common in adults, ~18,000 per year. Chronic lymphocytic leukemia (cll): most common in adults 55+, ~15,000 per year, can be asymptomatic for months or years.