BIOL 0170 Study Guide - Midterm Guide: Face Transplant, Facial Trauma, Xenotransplantation
7 Nov 2016
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No history of hiv or hep c, cancer for 5 years. Organ transplantation is not available for all patients who may require it. Patients who are unable to take immunosuppressive drugs. Hyperacute: recognition of donor endothelial cells by preformed recipient antibodies. Acute: direct pathway - t cells recognize intact allo-hla molecules on donor cells. Chronic/late acute: indirect pathway - t cells recognized processed allo- antigen. Inflammation: associated with surgery, always present initially and can add fire to any potential rejection reactions. Graft vs. host: after allogeneic bone marrow/stem cell transplant, donor cells view recipient"s body as foreign and attack the body. 1984 national organ transplant act: nationwide computer registry operated by united network for organ sharing, organ procurement. Organizations cover all costs related to organ donation. 1986 required request laws: require hospitals to identify patients and approach families about donation. 35% of potential donors don"t become donors because family members do not give consent.
