NURS 83PL Study Guide - Quiz Guide: Protamine Sulfate, Platelet Transfusion, Polycythemia Vera
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Surgery, local inflammation, cancer, thrombophilias, nephrotic syndrome, ibs, oral corticosteroids (ocs). 4. blood flow is reduced (platelet aggregation: fibrin strands form (coagulation cascade) Action: inhibits specific clotting factors to prevent formation of clots. Used for venous thrombi as they have more fibrin than platelets. Action: inhibit vitamin k synthesis, take few days for max effect. Therapeutic pt & inr = 2-3 (adults on warfarin) Food interaction: 4g, foods, green leafs & vegetables. Be consistent w/ vitamin k intake while on warfarin. Ci: gi ulceration, blood dyscrasias, severe kidney/liver disease, severe htn, polycythemia vera. Se: hit (heparin induced thrombocytopenia) it is an allergic reaction with a paradoxical occurrence of thrombosis. Used for arterial thrombi as they are formed under more shear condition and tend to have more platelets than fibrin. Se: bleeding, flu-like sx, ha, dizziness, bruising, rash. Action: dissolve clots convert plasminogen to plasmin, which digests fibrin clots.
