NEUROSCI 101 Study Guide - Midterm Guide: Eric Kandel, Petri Dish, Donald O. Hebb

• School: Duke University
• Department: Neuroscience
• Course: NEUROSCI 101
• Professor: Christina Williams

Document Summary

Understanding brain activity is key in understanding normal/abnormal behavior. Karl lashley searched for the location of a memory ( engram ) discovered memory in cortex was widely distributed; not where but rather how much . Experiment: lesions and cortical incisions in rats: more you remove, the more the patient forgets. Therefore, memory is : distributed in cortex, not isolated to a particular region of the cortex, cortical regions can substitute for each other, degree of impaired memory depends on extent of damage. Hypothesized that learning and its retention (memory) involves strengthening of. Automaticity/specialization developed at the level of the synapse. Strengthening of synapses by presynaptic changes in amount of neurotransmitter released postsynaptic changes in number/sensitivity of receptors structural changes in the synapse more synapses, bigger synapses, rearranges synapses, reduction of unfavorable synapses. Nobel prize for habituation research on apylsia gill reflex.