BIOL 4087 : Exam 1notes
Document Summary
Chapter 2 - water: h2o characteristics, noncovalent interactions, hydrogen bonds, electrostatic interactions, van der waals interactions. Ionization of water: ph, buffers, henderson-hasselbalch equation. Solvent of life : 60-70% of the weight of most organisms, determines shape and interactions of biological molecules, water is polar, *fig 2-1a, 2-1b. Part: hydrophobic tail if put into water the hydrophobic parts would hide from the hydrophilic and part hydrophobic. The hydrophobic stuff goes inside away from water and the hydrophilic is on the outside: hiv protease example valine substitutes for isoleucine, which does not have water . Vdw interactions and therefore does not work as an inhibitor. Water and amphipathic molecules ph and the ionization of water: h2o h+ + oh, keq = [h+][oh-] products concentration pure water concentration is 55. 5 m. Acids and bases: strong acids and bases will completely dissociate in water, hcl h+ + cl, naoh na+ + oh, weak acids and bases partly dissociate in water.
