BIOL 4105 : Para Exam1
Document Summary
Neutrophils (pmn"s) (multi-lobed nucleus) make up the largest percentage of circulating wbc"s [60%] (2) (3) (4) (5) (6) Lymphocytes mostly nucleus (2nd most abundant [30%]) Plasma spun down blood, bottom layer = fluid. Serum has antibodies/proteins, but other cells in fibrin clot can"t reverse clot. Both are really the same, but in serum the fibrinogen is gone because it formed the irreversible clot. (9) Professional phagocytes: (a) neutrophils and macrophages/monocytes: engulf particulate matter and try to destroy it (i) neutrophils --- seek, destroy, die: first on scence, non-dividing and short-lived. Grandules have hydrolytic enzymes to destroy via phagocytosis: produced in bone marrow (released during infection into blood) (ii) macrophages, killers/scavengers, clean up worn out cells, follow after neutrophils, long lived, will divide @ site (iii) Associated w/ allergies or parasite infections: allergic responses, more allergies/asthma when parasite levels are low (industrialized world) and vice versa, parasites can manipulate which way immune response goes.
