BIO_SC 2200- Midterm Exam Guide - Comprehensive Notes for the exam ( 14 pages long!)
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Bio_sci 2200: chapter 4 summary and vocab: garrod"s hypothesis of inborn errors of metabolism. Initiation of transcription at promoters: prokaryotes: promoter: a sequence upstream of the start of the gene that encodes the rna, the rna polymerase interacts with the promoter. The way the rna polymerase interacts, spatially speaking, defines the direction for transcription and, thus, dictates to the enzyme which dna strand and where transcription is to begin. About 9 bases of the new rna are bound to the single-stranded dna bubble, with the remainder exiting the enzyme in a single-stranded form. 3 the transcription initiation start site (defined as +1); and (2) the tata box, or tata element (also called the. The multi-subunit tfiid has one subunit called the tata-binding protein (tbp), which recognizes the tata box sequence and several other proteins called tbp-associated factors (tafs). In vitro, the tfiid-tata box complex acts as a binding site for the sequential addition of other transcription factors.