TOX 201 Study Guide - Spring 2019, Comprehensive Final Exam Notes - Liver, Poison, Methylmercury
29 Mar 2019
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5:29 pm: 1978 markov, shot by modified umbrella which shot out ricin, thigh felt tingly. Leads to asphyxiation: b12 can prevent toxicity, ricin, grows in warm areas, castor bean, poison is from the mashed part, untreated ricin is absorbed by cells but not if heated. Inactivates ribsomes: need 1-3 days for effect, changes depending on route of entry, orally: 20 mg/kg. 12:48 pm: 1950s, chisso corporation, excess of cats, acting eerily, manufacturing company responsible. Inhaling fumes: acetaldehyde, precursor to plastic, catalyst used: mercury, elemental mercury not terribly toxic. Inorganic mercury: positive charge 1 or 2, toxic. Ions: can cause personality change and shakes loss of sight and loss of consciousness, anaerobic bacteria, used sulfur as energy source. Dose response: hazard, potential harm, risk, realistic harm, more hazard, more risk, greater the dose, the greater to response. Important when something in small doses in good but in large very bad.
