GENE 540 Study Guide - Midterm Guide: Sister Chromatids, Dna Replication, Chromatin
Document Summary
Chromosome are dna protein structure that is in the nucleus (big bag of dna: distance between each base-pair is 0. 34 nm; number of base pairs is 3 billion. Dna is packaged with proteins (histones are common) chromatin: dna packaged with proteins. Dna wrapped around histones forms nucleosomes to get more of a compact structure; then nucleosomes come together more to get more of a compact structure. Nucleosomes consist of 147 base-pairs of dna wrapped around a core set of histone proteins. As this happens, the length of the dna gets shorter. During mitosis, chromosomes further condense to a form that is visible by light microscopy; When chromosomes go through mitosis, they condense even more we are able to see it in a light microscope. They are like this due to the cohesion complex (held together by cohesion during mitosis; before metaphase)
