PSYC 1250 Study Guide - Midterm Guide: Substance Dependence, Substance Abuse, Psychological Dependence
6 Oct 2018
School
Department
Course
Professor
Document Summary
In relation to everything else, how much of the visits due to these drugs. Therapeutic index of 50% of people taking the drug, how much of the drug is required to have an effect vs. the lethal dose. Ratio of ld50/ed50, you want a larger ratio. Margin of safety more conservative index of safety. If two drugs have the same margin of safety of therapeutic index, the one with the margin of safety is safer. (only 1% of people will experience toxicity vs 99% who experience the effects of the drug) Sensitization the more you take a drug, the more effective it becomes. Tolerance the more you take a drug, the less effective it becomes. Behavioral tolerance has to do with surroundings. Being in a familiar environment can increase craving but lessen effects of the drug. Acute effects of the drug felt right away.
