PHYSIO 3102 Study Guide - Final Guide: Bile Acid, Distal Convoluted Tubule, Enteropeptidase

• School: Ohio State University
• Department: Physiology and Cell Biology
• Course: PHYSIO 3102
• Professor: All

Document Summary

Making concentrated urine: occurs when water is reabsorbed, water moves out (180 l/day, kidneys produce hyperosmotic urine (relative to plasma, urine is higher) Start by flowing down descending limb (remember: bowman"s capsule-water, glucose, ions, water pct- water, glucose, amino acids, atp pulls back) Water can move at this point, but will not because there is no gradient yet. Lumen osm 300 = if osm 300 no change in osm, nacl moves out. Up ascending limb where nacl pumped to if, lumen osm decreases and if osm increases. New flow down d limb -lumen osm does not equal if osm increase lumen osm. Osmotic gradient in medulla (longer = higher gradient) Up to this point, this is only the set up! Need the collecting duct to pull from dct in cortex. Collecting duct moves through the medulla so this is a gradient. If permeable to water, urine will get concentrated, if impermeable to water, urine remains dilute.