BIOL 309 Study Guide - Quiz Guide: Mutation Rate, Dna Mismatch Repair

11) CIRCLE ALL CORRECT ANSWERS: Human males are hemizygous for

a) Sxl gene b) pseudoautosomal region of the Y c)SRY d) gene for testis determining factor e) Xist gene

12) The X inactivation center codes for

a) gonadal ridges to form ovaries b) gonadal ridges to form testes c) RNA d) testosterone e) protein enhancing transcription of sex linked genes

13) CIRCLE ALL CORRECT ANSWERS: The pseudoautosomal region is found on

a) autosomes in males b) autosomes in females c) X chromosome d) Y chromosome e) both the X and Y chromosome f) could occur in fruit flies

14) Comparing two monozygotic XX twins to two monozygotic XY twins

a) XX are more identical b) XY are more identical c) monozygotic twins do not occur

EXPLAIN YOUR ANSWER:

15) CIRCLE ALL CORRECT ANSWERS: Butterflies and Habrobracon differ in

a) which sex is homogametic b) which sex is monoploid c) one has sex chromosomes and the other does not d) one produces some gametes by mitosis, the other does not

___1. Nationally, the most common cause of Down Syndrome is
a. nondisjunction of Chromosome 21 during meiosis
b. translocation of Chromosome 21 onto another chromosome
c. inversion of a large section of Chromosome 21
d. deletion of the Down Syndrome gene
___2. In humans, sex is determined by
a. The presence or absence of the Y chromosome
b. The ratio of X chromosomes to sets of autosomes
c. The temperature during fetal development
d. Which parent is stronger at the time of conception
___3. A translocation is
a. a chromosomal abnormality in which a piece of one chromosome breaks off and attaches to a different chromosome
b. an abnormality in which the chromosomes are translocated out of the nucleus
c. a condition in which the chromosome has broken in two places and come back together with the middle segment backward
d. an abnormality in which there is an extra copy of one chromosome
___ 4. In snapdragons, a red-flowered plant crossed with a white-flowered plant produces all pink-flowered offspring. But crossing two pink-flowered plants produces red, pink, and white in a 1:2:1 ratio. This is a good example of
a. Incomplete dominance
b. Dominance of the red allele over the white allele
c. Lethal effects of the pink allele
d. Sex-linkage of the flower-color alleles
___ 5. If a person with type AB blood marries a person with Type O blood, what blood types are possible in their children? (Assume this trait is a single-gene trait, not complicated by interaction with other genes).
a. A, B, AB, or O
b. A or B only
c. AB or O only
d. AB only 2
___6. In what phase of meiosis are haploid nuclei first formed? a. Anaphase I b. Metaphase II c. Telophase II d. Metaphase I e. Telophase I
___7. What is the phenotype of a heterozygous tall pea plant? a. tall b. Tt c. TT d. tt e. dominant
___ 8. If genes A and B are far apart on a chromosome, and A and C are close together, which of the following observations is expected?
a. Crossing over will occur more often between A and C than between A and B
b. Crossing over will occur at equal frequencies between A and C, and between A and B
c. Crossing over will occur more often between A and B than between A and C
___9. Sometimes an organism’s genotype for one gene masks the effect of a different gene. This phenomenon is called
a. Dominance
b. Incomplete dominance
c. Co-dominance
d. Epistasis
e. Variable expressivity
___10. The dominant allele of a gene is
a. The one that is expressed most often in a population
b. The one that is expressed most often in any particular cross
c. The one that is expressed in an individual that has two different alleles
d. The one that is most healthy to have, that gives the greatest fitness
___11. In human cells, DNA replication occurs
a. In S phase of interphase
b. In G1 phase of interphase
c. In G2 phase of interphase
d. In prophase of mitosis
e. Whenever the cell needs to read the DNA to make proteins
___ 12. A process in which recipient cells take up genes from DNA molecules floating free in the surrounding medium is called
a. conjugation
b. specialized transduction
c. generalized transduction
d. transformation 3
___ 13. Most calico cats are female. However, a few rare males are observed. What is the genotype of a male calico cat?
a. X BX 0
b. X OY
c. X BY
d. X BYY
e. X BX OY
___ 14. A type of red-green color-blindness is a sex-linked (X-linked) recessive trait in humans. Can a woman have this type of color-blindness?
a. Yes, a woman could be color-blind if her mother and father were both heterozygous.
b. Yes, a woman could be color-blind but only if she has an abnormal number of sex chromosomes.
c. No, women can't show sex-linked traits because they lack a Y chromosome.
d. No, women can't show sex-linked traits because they have two X chromosomes.
e. Yes, a woman could be color-blind if her father was color-blind and her mother was a carrier (heterozygous).

Please provide brief (one sentence) answers:

a) The Mycoplasma chromosome codes for 500 genes, yet it has about 20 promoters. Provide a brief explanation for how this is possible.

b) How many seconds would it take the bacterial RNA polymerase to synthesize an mRNA of 5,000 bases?

c) How many mistakes would the bacterial RNA polymerase make while synthesizing an mRNA of 30,000 bases?

d) Sigma (?) protein by itself does not bind to promoter sites. Predict the effect on transcription of a mutation enabling ? to bind tightly to the –35 region in the absence of other subunits of RNA polymerase.

e) What is the structure of the most common transcription terminator signal in E. coli, and what are 2 conserved features of the RNA sequence of this structure?

f) Why is RNA synthesis not as carefully monitored for errors, as is DNA synthesis?