MIC 301 Study Guide - Spring 2018, Comprehensive Midterm Notes - Visceral Leishmaniasis, Virulence Factor, Virulence

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MIC 301
MIDTERM EXAM
STUDY GUIDE
Fall 2018
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Lecture 10:
Symbiosis- interaction between two different organisms living in close physical association,
most important in eukaryotes is the mitochondria
Parasitism- in order for the bacteria to survive the host must be harmed
Commensalism- by living in the host it can reproduce and grow, but the host goes unharmed
Mutualism- both the host and bacteria are able to benefit
Examples of parasitism: Vibrio Cholera
- Type: acute, possibly fatal
- Invasive: No
- Route: oral
- Toxigenic: yes
- Characteristic: dehydration
- Treatment: rehydration
- Attaches to the pilla and
destructs the host in order to
survive
Examples of parasitism: Mycobacterium tuberculosis
- Gram positive pathogen
- Type: chronic in most but asymptomatic, ⅓
of people have it, 10% of people develop
end stage disease (cholera is worse)
- Route: aerosol
- Toxigenic: No
- Treatment: antibiotics
Examples of parasitism: Chlamydia- obligate
intracellular pathogen
- Can cause problems with fertility if it goes into the
epithelial cells
- Two types: (type three secretion system)
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- EB: elementary body
- Protein synthesis, once in the cell it secretes it and turns to a raticular
body
- RB: raticular body
- Can turn back into EB after
Examples of commensalism: H Pylori- helical vectors
- Type: chronic, can lead to ulcer or cancer
- Invasive: minimally
- Route: Oral
- Toxigenic: No
- Characteristics: stays quiet, mechanism of dealing with stomach acidity
- Treatment: yes, antibiotic
- Can become parasitic if ulcer or cancer forms
Examples of mutualism and commensalism: Staph epidermidis
- Protects us from skin pathogens and inflammatory responses
Mutualist: mitochondria
- The mitochondria is a bacteria
Mitochondria vs Gram Negative
First Recognition of morphological similarity between mitochondria and bacteria
- Richard Altmann, Die Elementary Organismen, und ihre beziehungen zu den zellen in
[the cellular organelles and their relations to cells]
- Mitochondria is greek for mitos “thread” and chondrion “grain like”
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Document Summary

Symbiosis- interaction between two different organisms living in close physical association, most important in eukaryotes is the mitochondria. Parasitism- in order for the bacteria to survive the host must be harmed. Commensalism- by living in the host it can reproduce and grow, but the host goes unharmed. Mutualism- both the host and bacteria are able to benefit. Attaches to the pilla and destructs the host in order to survive. Type: chronic in most but asymptomatic, of people have it, 10% of people develop end stage disease (cholera is worse) Can cause problems with fertility if it goes into the epithelial cells. Protein synthesis, once in the cell it secretes it and turns to a raticular body. Type: chronic, can lead to ulcer or cancer. Characteristics: stays quiet, mechanism of dealing with stomach acidity. Can become parasitic if ulcer or cancer forms. Protects us from skin pathogens and inflammatory responses. First recognition of morphological similarity between mitochondria and bacteria.

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