BIO SCI E124 Study Guide - Midterm Guide: Mertens-Stable Equilibrium, Basic Reproduction Number, Cyclic Model
Document Summary
Dynamics of epidemic are faster than birth and death of individuals. Population is well-mixed an infected individiaul can infect any scuscpetible in the population (no spatial effects). *total population does not change with time: n = s(t) + i(t) + r(t). Although population of internal variables may vary the overall population wont hange. *based on assumptions of no death, no birth, disease is not lethal. # of infections by sick person before it recovers. R0 (reprodcution #) > 1 there is epidemic outbreak. Probability per unit of time of infection: bis. Probability per unit of time of recovery: yi. Can get infected multiple times (immunity wears off. ) Viruses designed to infect and kill cancer cells. Can target cells with mutations in p53 gene. Adegfpuci, a virus that makes cells glow green to track viral speed. With low initial virus loads and identical initial conditions, two outcomes were seen: Limited infectionss (slow viral growth that eventually stalled and regreessed. )