MCB 1405 Study Guide - Midterm Guide: Frederick Griffith, Martha Chase, Common Rule

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Exam i review sheet (wednesday february 22, 2017) Format of the exam: multiple choice, definitions, short answer, essay. Define genetic engineering: the deliberate modification of the characteristics of an organism by manipulating its genetic material. How was dna discovered to be the genetic material: alfred hershey and martha chase. Frederick griffith transformation (genetic alteration of a cell) found that something transformed it: mice experiment. Hershey and chase transforming agent = dna took everything griffith put i mice and put it in dnase and rnase: dna as genetic material, proved it was dna not protein. Describe the complex regulation of operons in bacterial cells. (hint: repressors and enhancers: operons: prokaryotic. What is a gene: binding site, promoter, exon (coding regions), intron, cut out introns because they don"t code anything, part of a chromosome (dna) that codes for a specific protein. What three events have to happen in order to get a functional mrna transcript from a primary transcript: g-cap, poly-a-tail, splicing.