MCB 2210 Study Guide - Final Guide: Pericentriolar Material, Spindle Apparatus, Basal Body

• School: UConn
• Department: Molecular and Cell Biology
• Course: MCB 2210
• Professor: David Daggett

Document Summary

Specialized cells (flagella + cilia), slide set 23, qs #86-102, 118-120. Microtubules nucleate out of the pericentriolar material surrounding centrioles (by gamma-turc) but do not nucleate from the centrioles themselves. Found in the mitotic spindle, cilia, flagella, centrioles, centrosome, etc. Mtoc - nucleates and organizes cellular microtubules. (-) end of microtubules are embedded in the mtoc while the (+) end of microtubules face the cytosol. Centrosomes, flagella basal bodies, cilia basal bodies have them. Centrosomes is a mtoc centrosomes are a pair of centrioles centrioles can function as the basal bodies of primary cilia and flagella. Cytoplasmic microtubules do not directly radiate from the ends of centrioles. Centrosome = a perpendicular pair of centriole + pericentriolar material + gamma- Can function as the basal body of primary cilia and flagella. 9 triplets arranged like a pinwheel without central microtubules (9+0) Moving a cell from place to place (motile) Move fluid and particulate material past a cell (motile)