BISC439- Midterm Exam Guide - Comprehensive Notes for the exam ( 22 pages long!)
12 Oct 2017
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Developmental neurobiology chapter 18 class notes: programmed cell death requires rna and protein synthesis, neurotrophic hypothesis, ngf binds to receptors on the axon terminals a. i. Terminals that bind to enough ntfs will survive a. ii. Ntf travels retrogradely up the axon and affects gene expression in the nucleus a. ii. 1. Injecting exogenous ngf can rescue neurons that would otherwise die b. i. Had to be injected close to the axon terminals b. ii. You can"t kill off motorneurons by knocking out just one receptor or neurotrophin b. ii. 1. Membrane proteins communicate with schwann cells: phenotype specification a. In normal dna the chromosomes are large and heavy a. i. In apoptotic cells, dna is fragmented and chopped up b. i. Developmental neuro paper 7 notes: lmpcr is much more sensitive than normal pcr; amplifies dna exponentially, fig. 1 thymus is known to undergo pcd: clusters of dying t cells that are overreactive and could be toxic, dexamethasone induces apoptosis, d-f: retinal ganglion cells postnatally.
