HUN 4446- Midterm Exam Guide - Comprehensive Notes for the exam ( 47 pages long!)
16 Feb 2018
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Nutritional genomics: the future of nutrition & medical practice. Improvements in medicine: pigs used to help people with hemophilia, designer drugs, people respond differently to different drugs, more accurate risk assessment, more accurate prediction of response to medicine, tailored nutrition therapy, genetically modified foods. January 16, 2018: nutrigenetics and nutrigenomics, nutrigenetics = how an individual"s genetic makeup affects utilization and response to dietary components. Impaired function increases blood homocysteine concentration: substitution c t occurs at basepair. 677: valine gets coded for instead of alanine, less synthesis of mthfr. Implications: mthfr 677 tt genotype + impaired folate status = 5 fold higher ntd risk, ntds = spina bifida, anencephaly, not all women with this snp. Will have an ntd pregnancy (they just have higher susceptibility: may have protective effect genotype for colorectal cancer. Diseases and disorders of the upper gi tract: part 1. Diseases of the upper gi tract: part 2.
