[UC 154] - Midterm Exam Guide - Ultimate 28 pages long Study Guide!

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5 Oct 2016
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Dna replicates just like cellular dna - these viruses can use cellular replication (dna polymerase) or make their own dna polymerase or some will use both. Viruses with rna genomes viral rna chromosomes are called segments o they can have either strand of the rna (+)(-) some are called (+) strand same as mrna. More complex because they have to go through more steps to replicate (because they have a single stranded genome) Rna genome but they replicate through a dna intermediate* o replicates via a double stranded dna intermediate. Most rna viruses replicate in the cytoplasm: use their own rna polymerase - don"t need the cell nucleus, notable exceptions. Capsids usually symmetric - facilitates assembly and disassembly of the viral particle. Metastable structures o stable enough to survive outside cell: unstable enough to come apart upon infection of new cell - allows it to replicate.

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