BIOL 330 Study Guide - Quiz Guide: Gene Conversion, Intron, Pseudogene

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6 Nov 2018
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Detached or attached earlobe: genetic drift: mechanism of evolution in which allele frequency of a population changes over generation due to chance (sampling error, ex. Stepping and killing insects on the sidewalk by accident: has bigger impact on small population because there are less. Selection can be detected by measuring sequence variation: the ratio of nonsynonymous to synonymous substitutions in the evolutionary history of a gene is a measure of positive or negative selection. If ratio =1, neutral selection: age of allele can be estimated by looking at the number of synonymous mutations. Intron late model: hypothesis that the earliest genes did not contain introns, and that introns were subsequently added on some genes. Blue eyes vs. brown eyes: humans are estimated to have 20,000 pseudogenes, pseudogenes are nonfunctional gene copies that come in two varieties, processed pseudogenes result from reverse transcription (makes cdna from rna) and integration of mrna transcripts.

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