BIOLOGY 1A03 Chapter Notes - Chapter 5: Noncoding Dna, Oligonucleotide, Genetic Linkage

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BIOLOGY 1A03 Full Course Notes
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BIOLOGY 1A03 Full Course Notes
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Different types of dna sequences can lead to genetic variation. Different dna sequences and variations are prevalent within and across various populations. Tandem repeats: can be several thousand nucleotides in length and be present next to each other in multiple identical or near identical copies. Simple sequence repeats: repeats as short as 2 nucleotides. Not all variations in the genome have an observed affect. The outcome of a variation depends on the exact nature of the change and where in the genome the change occurs. A dna polymorphism is one of two or more alternative forms (alleles) at a chromosomal region (locus) that differs in either a single nucleotide base, or have variable numbers of tandem repeats. A large number of polymorphisms reside in non-coding dna, they can be used to assemble a high-density genetic map, referred to as dna markers.

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