BIOL 102 Chapter Notes - Chapter 7: Chemical Bond, Endergonic Reaction, Enthalpy
Document Summary
Metabolism/chemical reactions: metabolism: sum total of all chemical reactions that occur in organism, chemical reactions depend on: o direction o rate, energy: ability to promote change o kinetic: movement (ex. : motor protein walking" along microtubule) o potential: energy from structure/location/molecular bonds (ex. : gradient: thermodynamics: energy being converted from one type into another, first law of thermodynamics. Energy can"t be created or destroyed: second law of thermodynamics. High energy compound! (free energy substrate > product: electrons in free phosphate resonate, breaking bonds doesn"t create energy energy made available from formation of new products. Amino acids, side chains etc conform to right shape to bring to active site and manipulate change. Conformational change stabilized by intermolecular forces made by compound: temperature and ph affect structure/function of protein/enzymes. Substrate binding: high affinity = low km (michaelis constant) o km = substrate concentration at half-max speed. Inihibit ability ot bind: non competitive inhibitors o.
