PSYC 370 Chapter Notes - Chapter 15: Tachycardia, Morphine, Insomnia
Document Summary
Drug tolerance: of exposure to the drug: cross tolerance: tolerance to the effects of one drug that develops as the result of exposure to another drug that acts by the same mechanism, drug sensitization: an increase in the sensitivity to a drug effect that develops as the result of exposure to a drug, drug tolerance often develops to some effects of a drug but not others (ex. tolerance to nausea but not other aspects, no single mechanism responsible for drug tolerance, two categories of change underlie drug tolerance: Functional tolerance: tolerance resulting from a reduction in the reactivity of the nervous system (or other sites of action) to a drug: most common effect for psychoactive drugs, reduces number of receptors for drug, decreases efficiency with which it binds to existing receptors, or diminishes the impact of receptor binding on the activity of the cell.
