BIO152H5 Chapter Notes - Chapter 11: Spindle Apparatus, Sister Chromatids, Kinetochore
Document Summary
Mitosis and cytokinesis is responsible for growth, wound repair and reproduction. G1 phase, s (synthesis) phase- dna synthesis, g2 phase. Key events of cell cycle are: replication of hereditary material in chromosomes, partitioning of copied chromosomes to the two daughter cells during m phase. Gap phases important because cells replicate organelles, manufacture additional cytoplasm, grow large enogh and synthesize enough organelles that its daughter cells will be normal in size and function. Mitosis results in the division of replicated chromosomes and the formation of two daughter nuclei with identical chromosomes and genes. Eukaryotic chromosomes normally exist as long threadlike strands consisting of dna associated with globular proteins called histones. In eukaryotes the dna-protein material is called chromatin. Chromatid: each of the dna copies in the replicated chromosomes. Joined together along entire length as well as specialized region called centromere. Sister chromatids represent exact copies of the same genetic info.
