BIOA01H3 Chapter Notes - Chapter 3&13: Frederick Griffith, Ribonuclease, Deoxyribonuclease
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BIOA01H3 Full Course Notes
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Lecture 1: chapter 3 (3. 1 3. 2), chapter 13 ( 13. 4) Hereditary info is transmitted through dna first exp. To show that molecules transfer information through dna was done by frederick griffith. Virulent bacteria injected into rat rat died. Non-virulent bacteria strain injected into rat rat lived. Killed virulent bacteria injected into rat rat lived. Bacteria strain mixed rat died: conclusion: one strain of non-virulent bacteria can be transformed into virulent bacteria by an unknown molecule called the transforming principle. Mcleod experiment showed which molecule is responsible for the transformation. Mixed non-virulent w/ dead virulent and added rnase virulent. Mixed non-virulent w/ dead virulent and added protease virulent. Mixed non-virulent w/ dead virulent and added dnase non-virulent: conclusion: dna is responsible for transforming bacteria. Dna molecules are copied during replication allows genetic information from one. Unrepaired errors result in mutations a mutation in dna of virus creates virulent and non-virulent strains. Dna specifies sequence of amino acids affects its 3-d structure.
