PSYB55H3 Chapter Notes - Chapter 8.24: Striatum, Subthalamic Nucleus, Pars Compacta
Document Summary
Parkinson"s disease incl"s disorders of posture + locomotion, hypokinesia (the absence or reduction of voluntary mvmnt), and bradykinesia (slowness in initiating and executing mvmnt). Parkinson"s disease b/c it can compensate for the loss of endogenous dopamine. Deep-brain stimulation is a surgical technique in which electrodes are implanted in the brain. This procedure has become a novel treatment for. Implants are usually placed in the subthalamic nucleus. The basal ganglia may play a gen func in state changes. For the motor system, a state change would correspond to the initiation of a new mvmnt. In the cogn system, a state change could be a change in mental set, such as when we change from 1 goal to another. Dopamine acts as a reinforcement signal to bias some states over others. The output from the basal ganglia, via thalamic projections, influences activity in the cortex, including the motor cortex. All the output signals from the basal ganglia are inhibitory.
