PSYC33H3 Chapter Notes - Chapter 5.2: Internal Validity, Clinical Trial, Statistical Significance

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5 May 2016
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Single-subject designs as a tool for evidence-based clinical practice: are they unrecognized and. Clinical case description/report: considered analogous to the case series of a group design and represents the lowest level of sophistication of single-subject methodology: limitations: change in outcome/response cannot be unequivocally attributed to treatment because . Introduction of treatment is generally not systematically manipulated. There is usually no attempt to investigate or control for stability of responses. There is no control for extraneous events that might influence outcome. Threaten internal validity which diminish the capacity to attribute any change in the patient"s condition to the treatment per se. Muli-phase (>2 phases) and multiple baseline designs: enhance potential control of extraneous factors given that the effect of the confounding even can be least be observed across several treatment and baseline phases: pros. Replication through patients, therapists or settings diminishes the likelihood that a particular extraneous even will universally affect outcomes.

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