PSYC62H3 Chapter Notes - Chapter 10: Alprazolam, Neurodegeneration, Flumazenil
Document Summary
Spirits are produced from concentration (distillation) of fermented solutions, and have a higher alcohol content (more than 20%) The alcohol content is specified in terms of proof, which is exactly double the actual percentage of ethanol a beverage contains. Not very potent drug, requiring several grams to exert noticeable effects on behaviour, rather than milligram. Takes between 25mg and 50mg of ethanol per 100 milliliters of blood (a blood alcohol content, or. Bac, of 0. 025% to 0. 05%) to exert measurable effects in most individuals. Legal bac limits for driving: between 0. 0% and 0. 05% Alcohol also has somewhat different pharmacokinetic properties than most other drugs. Ethanol molecule is small, neutrally charged molecule it is readily absorbed from all compartments of the gi tract. Readily passes through the blood-brain barrier and placenta due to sufficiently high oil/water partition coefficient same amount of booze is ingested and they weigh the same.
