PSY372H1 Chapter Notes - Chapter 3: Degenerative Disease, Glioma, Intracranial Pressure
Document Summary
Confabulation may occur where an individual develops a cover story or excuse for the lack of memory. The individual may become geographically lost or wander and may engage in activities which are dangerous to self or others. Sundowning: in patients with dementia, the worsening of symptoms as the day progresses. Alzheimer"s type dementia (ad: the most common form of cortical decline, alzheimer"s type dementia is characterized by neurofibrillary tangles and amyloid plaques. A clear diagnosis can"t be made until autopsy by is termed alzheimer"s type based on behavioural symptoms, neuroimaging and neurochemical profiling. It"s hard to see the tangles and plaques on any form of brain scan: neurofibrillary tangles are composed of tau protein tangles of dead tissue in the brain. They develop when microtubules which transport sustamces from the soma to the end of the axon- become twisted. They are made of an amino acid peptide protein core called beta0amyloid.
