Psychology 2221B Chapter Notes - Chapter 10: Paraplegia, Adrenal Medulla, Mptp

• School: Western University
• Department: Psychology
• Course: Psychology 2221B
• Professor: Shelley Cross- Mellor

Document Summary

Infections of the brain: encephalitis- resulting inflammation brain infection. Bacterial infections: cerebral abscesses- pockets puss in brain, major cause meningitis (inflammation meninges) fatal 25% adults, antibiotics can eliminate bacterial infections, not reverse damage, general paresis- syndrome insanity and dementia results syphilitic infection. Viral infections: particular affinity neural tissue and those that attack neural tissue no greater affinity, rabies, mumps and herpes. Involvement etiology (cause) disorders often difficult recognize lie dormant many years. Neurotoxins: toxic psychosis- chronic insanity produced by neurotoxin (mercury/ lead permanently damage brain, drugs used to treat neurological disorders= toxic effects ex: tardive dyskinesia (td, endogenous- produced by patient"s own body, can cause brain damage. Immunomodulatory drugs (1990s)= slight bens only some patients, stimulated search more effective drugs. Transgenic mouse model of alzheimer"s disease: transgenic- animals genes other species introduced, gene mutations promote accumulation human amyloid injected newly fertilized mouse eggs, injected into foster mouse mother= comparable humans, no neurofibrillary tangles= inject genes promote tau accumulation.