Psychology 2221B Chapter Notes - Chapter 18: Orphan Drug, Amygdala, Diazepam

• School: Western University
• Department: Psychology
• Course: Psychology 2221B
• Professor: Shelley Cross- Mellor

Document Summary

Chapter 18- biopsychology of psychiatric disorders: psychiatric disorders- disorders of psychological function sufficiently severe to require treatment, dif diagnose= dsm-iv-tr, patients suffering same disorder display different symptoms, different disorders display many same symptoms. Schizophrenia: breakdown integration among emotion, thought and action, ass concept madness= 1% adolescence/ early adulthood. Causal factors in schizophrenia: close biological relative= 10%, concordance rate mz (45%) and dz (10%), adoption studies= risk increase presence biological parents not adoptive. Inherit potential which may/ may not be activated by experience: genes act in combination one another and experience produce disorder, mechanisms not determined, early experiential factors= alter normal course neurodevelopment, leading if susceptible. Atypical neuroleptics: drugs effective against schizophrenia w/o binding strongly to d2 receptors, clozapine= d1 and d4 receptors, several serotonin and histamine receptors, slight. D2 receptors: differ therapeutic efficiency and production side effects, don"t differ substantially from first-gen, some effective d2 receptor antagonists have no antischizophrenic effects and drugs block effects glycine/ glutamate= effective preliminary tests.