PS263 Chapter Notes - Chapter 12: Cortisol, Long-Term Memory, Sensory Neuron
Document Summary
Module 12. 2 storing information in the nervous system. Synapse that increases in effectiveness because of simultaneous activity in presynaptic and postsynaptic neurons is called a hebbian synapse. Strong stimulation on the skin excites a facilitating interneuron that releases serotonin onto presynaptic terminals of many sensory neurons which blocks potassium channels in these membranes. Result is that after later action potentials, membrane takes longer than usual to repolarize so presynaptic neuron continues releasing its neurotransmitter for longer than usual. Repeating this process causes sensory neuron to synthesize new proteins that produce long term sensitization. Long term potentiation is when one or more axons connected to a dendrite bombard it with a rapid series of stimuli and bursts of intense stimulation and leaves some of the synapses potentiated for minutes, days or weeks. Ltp shows three properties that make it an attractive candidate for the cellular basis of learning and memory:
