PSC 434 Chapter Notes - Chapter 19: Angiotensin Ii Receptor Blocker, Renal Sodium Reabsorption, Calcium Channel Blocker
17 Feb 2019
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Antihypertensive drugs: diuretics: bumetanide, furosemide, hydrochlorothiazide, spironolactone,triamterene, Chlorthalidone: beta-blockers: atenolol, labetalol, metoprolol, nadolol, propranolol, timolol, ace inhibitors: benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, quinapril, Ramipril: angiotensin ii-receptor antagonist: losartan, calcium channel blockers: amlodipine, diltiazem, felodipine, isradipine, nicardipine, Nifedipine, nisoldipine, verapamil: alpha blockers: doxasozin, prazosin, terazosin, other: clonidine, diazoxide, hydralazine, labetol, alpha-methyldopa, minoxidil, sodium nitroprusside, reserpine. In contrast, loop diuretics are good diuretics but poor antihypertensives (unless renal failure is present): thiazide diuretics, thiazide diuretics, such as hydrochlorothiazide, lower blood pressure initially by increasing sodium and water excretion. It has the additional benefit of reducing the cardiac remodeling occurring in heart failure: thiazide diuretics are particularly useful in the treatment of black or elderly patients. They are not effective in patients with inadequate kidney function: thiazide diuretics are orally active, se: thiazide diuretics induce hypokalemia (monitor for cardiac arrythmias!) and hyperuricemia in. 70 % of patients and hyperglycemia in 10 %.
