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MCELLBI C61 Chapter Notes - Chapter 6: Protein Kinase, Cyclic Adenosine Monophosphate, Axon Hillock

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sapphirerat478
19 Nov 2016
School
Berkeley
Department
Molecular And Cell Biology
Course
MCELLBI C61
Professor
David Presti

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Document Summary

Electrical synapse: gap junction, connexins, connexons: build from clusters of proteins that form channels in the membranes of two adjacent cells. Connexins are component proteins that make up connexons. Connexons join together to form an electrical synapse, allowing ions to pass directly from one cell to the next. Fast propagation of membrane potential charges from one cell to another and transfer of small molecules having regulatory functions within cells. Chemical synapse: complex opportunities for additional kinds of regulation. Changes in strength, feedback, and varied effects on different target cells. When the term synapse is used without further qualification, it refers to a chemical synapse. Synaptic vesicle: within the axon terminal are numerous small spheres formed of lipid bilayer membrane. These are synaptic storage vesicles, each filled with several thousand neurotransmitter molecules. Specific proteins in the lipid membrane of vesicles attach some of the vesicles to other proteins in the boundary membrane of axon terminal.

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Related Questions

The junction specialized for the transmission between a neuron and another cell is called a (1) _____ ______. Usually, the signal being sent to the receiving cell is carried by chemical messengers called (2) _____. (3) _____ is an example of this type of chemical messenger, which diffuses across the synaptic cleft, combines with protein receptor molecules on the muscle cell membrane, and soon thereafter is rapidly broken down by enzymes. At an (4) ____ synapse, the membrane potential is driven toward the threshold value and increases the likelihood that depolarization and an action potential will occur. At an (5) ____ synapse, the membrane potential is driven away form the threshold value, and the receiving neuron becomes hyperpolarized and is less likely to achieve an action potential. A specific transmitter substance can have either excitatory or inhibitory effects depending on which type of protein channel it opens up in the (6) ____ membrane. (7) ____ are neuromodulators that inhibit perceptions of pain and may have roles in memory and learning, emotional states, temperature regulation, and sexual behavior. (8) ____ ________ at the cellular level is the moment-by-moment tallying of all excitatory and inhibitory signals acting on a neuron. Incoming information is (9) ____ by the cell bodies, and the charge differences across the membranes are either enhanced or inhibited. Some narrow-diameter neurons are wrapped in lipid-rich (10) _______ produced by specialized neuroglial called Schwann cells; each of these is separated from the next by a(n) (11) ________ ________ - a small gap where the axon is exposed to extracellular fluid. A (12) ____ is an involuntary sequence of events elicited by a stimulus. During a (13) _______ ________, a muscle contracts involuntary whenever conditions cause a stretch in length; many of these help you maintain an upright posture despite small shifts in balance. Imbalances can occur at chemical synapses; a neurotoxin produced by Clostridium tetani blocks the release of GABA and glycine, thus freeing the motor neurons from (14) _____ control, which may cause tetanus – a prolonged, spastic paralysis that can lead to death. A. Excitatory H. Stretch reflex B. Inhibitory I. Summed C. Myelin J. Neurotransmitters D. Chemical synapse K. Postsynaptic E. Synaptic integration L. Endorphins F. Exposed node M. Acetylcholine (ACh)