BIOLOGY 201L Chapter Notes - Chapter 14: Nadh Dehydrogenase, Atp Synthase, Oxidative Phosphorylation

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14 Dec 2016
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Chapter 14 - energy generation in mitochondria and. Need a membrane, depends on electron-transport process that drives transport of protons across inner mitochondrial membrane. Stage 2: protons flow back down electrochemical gradient through atp synthase which catalyzes synthesis of atp. Above mechanism is chemiosmotic coupling - links chemical bond-forming rxns that synthesize. Atp with membrane transport processes that pump protons. Fadh2 and nadh donate high-energy electrons to etc and become oxidized. Electons are passed to o2 to form water. Has inner and outer membrane which create matrix and intermembrane space. Outer membrane has transport proteins called porins which form aqueous channels through lipid bilayer. Inner membrane is impermeable to ions and most small molecules. Site of oxidative phosphorylation and has proteins of electron transport chain, proton pumps, and. Has transport proteins that allow entry of selected small molecules: pyruvate, fatty acids. Inner membrane forms folds called cristae which increase surface area of membrane.

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