MCB 3020 Chapter Notes - Chapter 21: Reverse Transcriptase, Alternative Splicing, Microbiology
Document Summary
Identify which rna viruses use rna-dependent rna polymerases and which use. How do rna viruses replicate their genomes: methods vary from group to group. Dsrna, + sense, and - sense ssrna viruses use an rna-dependent rna polymerase to create a template intermediate of their genome. This template can then be used by the same enzyme to create more genome copies. Retroviruses use reverse transcriptase enzymes to convert their rna genome into a dna intermediate. This intermediate is transcribed into more genome copies by a. How do viruses use the least genetic material to create their proteins: methods vary. Overlapping coding regions with independent start/stop signals. Production of large polyproteins, cleaved by proteases (cid:858)read-through,(cid:859) not stopping at a stop codon. Reproduction of rna phages: rna genomes cannot rely on host cell enzymes for genome replication or mrna synthesis, rna-dependent rna polymerase completes life cycles replicase and transcriptase activities. Rotaviruses: human rotavirus kills >600,000 children worldwide each year transmitted by fecal material.
